About Pfam

Pfam version 36.0 was produced at the European Bioinformatics Institute using a sequence database called Pfamseq, which is based on UniProt release 2022_05.

If you find Pfam useful for your research, please cite the latest Pfam publication found in this list. Links to the Pfam documentation and publications are available in the Help/Documentation section in the InterPro website.

Pfam is freely available under the Creative Commons Zero (“CC0”) licence.

Pfam is powered by the HMMER3 package written by Sean Eddy and his group at HHMI/ Harvard University.

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Pfam is supported by the following organisations:

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EMBL is EMBL-EBI’s parent organisation. It provides core funding (staff, space, equipment) for Pfam.

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The Wellcome Trust has supported Pfam since the database inception, via core funding when based at the Wellcome Trust Sanger Institute. As well as providing and maintaining the campus on which the EMBL-EBI is located, the Wellcome Trust also now provides significant funding for Pfam (grant 221320/Z/20/Z). The current grant runs from October 2020 to September 2025.

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BBSRC is supporting Pfam activities (BB/X012492/1) from January 2024 to December 2027, and has previously supported Pfam activities via grants BB/L024136/1, BB/N00521X/1, and BB/S020381/1.

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The Howard Hughes Medical Institute supports the Eddy group.

Many organisations have supported Pfam activities in the past.

For more information, please contact the Pfam helpdesk.